A fundamental feature of the life of Anfrosina was the long suffering caused by a serious illness that led to her death within a few years. Despite the suffering, she lived a life of prayer and sacrifice by example and word.
Initially she became ill with appendicitis. After being operated on she continued to suffer, having trouble swallowing. Due to yet another problem she had another operation, with little chance of survival.
After receiving her First Communion and Confirmation, on 13 October 1932, Anfrosina spent the last five months of her life in bed, almost without being able to feed.
She died on 13 March 1933, surrounded by her family and many people, attracted by the fame of her spiritual life.
